biOptimizers - Magnesium Breakthrough

Promotes Heart Health

Magnesium is extremely important for heart health^[2] and blood vessel health. Magnesium deficiency seems to worsen the inflammation, blood vessel constriction, blood clotting, and stress responses that trigger heart conditions. Correcting deficiency appears to improve heart health and reduces risk of deaths, although it is unclear whether supplementation alone is sufficient to treat these conditions.*

Improves the Ability to Deal With Stress and Helps to Relax

A magnesium supplement significantly reduced stress^[3] in people who are deficient in magnesium. Also, combined^[4] with vitamin B6 was 40% more helpful than alone for severe stress. Findings support the need for magnesium supplementation for people living in conditions of chronic stress.*^[5]

Helps With Mood, Cognitive Function, and Mental Health

A magnesium supplement significantly improved^[6] mood^[7] after 2 weeks. Another trial found that magnesium supplements improved^[8] mood in seniors with type 2 diabetes.*

Promotes Healthy Blood Sugar Hormone Function And Promotes Healthy Metabolism

Magnesium is important for hormones that regulate bloog sugar^[9] to function well. Therefore, many people with blood sugar issues,^[10] metabolic syndrome, and diabetes are deficient in magnesium. Even when diabetes^[11] is well-controlled, a supplement would still be necessary to achieve healthy levels. In a clinical trial involving 65 diabetes patients, magnesium supplementation promotes healthy function^[12] and metabolism.*

A large-scale systematic and dose-response analysis found that magnesium supplementation correlated with reduced body weight^[13] and waist circumference among specific groups of people. Those with resistance, hypertension, obesity, magnesium deficiency, and women seem to weigh less and had smaller waist circumference if they took magnesium supplements.*

In pregnant women with gestational diabetes^[14], magnesium supplementation improved blood glucose control and pregnancy outcomes.*

Supports exercise performance and recovery

Magnesium supplementation improves speed and strength,^[15] possibly by making glucose metabolism more efficient. It also supports the necessary stress response to exercise, reduces muscle damage,^[16] and improves exercise recovery (400 mg/day, taken at breakfast).*

Improves Sleep Quality

In a small clinical trial involving 46 elderly subjects with insomnia,^[17] 500 mg of daily magnesium supplement reduced insomnia scores, sleep latency, and cortisol. Subjects also had more serum melatonin, slept deeper, and were less likely to wake up in the middle of the night.*

Builds Stronger Bones

Magnesium is a key building blocks of your bones.^[18] Magnesium deficiency can contribute to osteoporosis by:

• preventing healthy bone formation, creating brittle bones*
• causing low-grade inflammation*
• increasing cortisol, which can contribute to bone loss*
• reducing parathyroid hormone*

In a clinical trial^[19] involving 73,684 postmenopausal women, low magnesium intake was associated with lower bone density in the hip and whole body. Magnesium intake slightly higher than the Recommended Dietary Allowance was associated with lower arm and wrist factures from falling.*

Promotes Healthy Blood Pressure

A meta-analysis of 34 randomized control trials found that magnesium reduced blood pressure.^[20] However, the effect size is clinically small (<2 mmHg). Therefore, it may be good for supporting overall health and healthy blood pressure, but you may also need other interventions to achieve healthy blood pressure levels.*

Promotes Balanced and Healthy Immune System

Magnesium deficiency^[21] increases inflammation.^[22] In a meta-analysis^[23] involving 32,198 people, those with more magnesium had less serum C-reactive protein (a marker of inflammation).*

Overall, magnesium deficiencies tend to exacerbate or increase the risk of conditions that involve chronic inflammation.^[24]

Supports Vitamin D Activation and Metabolism

Both Vitamin D and magnesium have important roles in bone health, immune function, and metabolism. Magnesium is a cofactor in vitamin D conversion and activation.^[25] Some people cannot increase their blood 25-hydroxy vitamin D levels despite supplementing with vitamin D3 because they are deficient. In other words, magnesium deficiency can make vitamin D ineffective.*

Also, in people deficient, high doses of vitamin D3 could worsen magnesium deficiency and increase the potential for side effects of vitamin D3, such as having calcium deposits in the arteries.*